1st » Christopher Columbus becomes the first European to visit what is now Venezuela.
17th » Cesare Borgia, son of Pope Alexander VI, becomes the first person in history to resign the Cardinal (Catholicism) or cardinalate. On the same day, the French King Louis XII names him Duke of Valentinois.
26th » Michelangelo is commissioned to carve the Pietà (Michelangelo) named Pietà .
29th » Vasco da Gama decides to depart Kozhikode called Calicut and return to Kingdom of Portugal.