7th April » Ferdinand Magellan arrives at Cebu (island) known as Cebu.
17th April » Trial of Martin Luther over his Lutheranism called teachings begins during the assembly of the Diet of Worms. Initially intimidated, he asks for time to reflect before answering and is given a stay of one day.
18th April » Trial of Martin Luther begins its second day during the assembly of the Diet of Worms. He refuses to recant his Lutheranism or teachings despite the risk of excommunication.
23rd April » Battle of Villalar: Charles V, Holy Roman Emperor known as King Charles I of Spain defeats the Revolt of the Comuneros or Comuneros.
27th April » Battle of Mactan: Explorer Ferdinand Magellan is killed by natives in the Philippines led by chief Lapu-Lapu.
29th April » Swedish War of Liberation: Swedish troops under Gustav Vasa defeat a Danish force under Didrik Slagheck in the Battle of Västerås and soon capture the city of Västerås. The Danish-held castle, however, does not surrender to the Swedes until 31 January the
17th May » Edward Stafford, 3rd Duke of Buckingham, is Capital punishment e.g executed for treason.
20th May » Ignatius Loyola is seriously wounded in the Battle of Pampeluna.
25th May » The Diet of Worms ends when Charles V, Holy Roman Emperor, issues the Edict of Worms, declaring Martin Luther an outlaw.
30th June » Spanish forces defeat a combined Kingdom of France named French and Kingdom of Navarre known as Navarrese army at the Battle of Noáin during the Spanish conquest of Iberian Navarre.
13th August » After Fall of Tenochtitlan e.g an extended siege, forces led by Spanish conquistador Hernán Cortés capture Tlatoani Cuauhtémoc and conquer the Aztec capital of Tenochtitlan.
23rd August » Christian II of Denmark is deposed as king of Sweden and Gustav I of Sweden called Gustav Vasa is elected regent.