15th January » King Francis I of France gives Jean-François Roberval a commission to settle the province of New France (Canada) and provide for the spread of the "Holy Catholic faith".
12th February » Santiago, Chile is founded by Pedro de Valdivia.
7th April » Francis Xavier leaves Lisbon on a mission to the Portugal named Portuguese East Indies.
8th May » Hernando de Soto reaches the Mississippi River and names it 'Río de Espíritu Santo'.
26th June » Francisco Pizarro is assassination called assassinated in Lima by the son of his former companion and later antagonist, Diego Almagro the younger. Almagro is later caught and executed.
23rd August » French explorer Jacques Cartier lands near Quebec City in his third voyage to Canada.
29th August » The Ottoman Turks capture Buda, the capital of the Hungarian Kingdom.
11th September » Santiago, Chile, is destroyed by indigenous warriors, led by Michimalonco.
13th September » After three years of exile, John Calvin returns to Geneva to reform the church under a body of doctrine known as Calvinism.
30th September » Spanish conquistador Hernando de Soto and his forces enter Tula people named Tula territory in present-day western Arkansas, encountering fierce resistance.
10th December » Thomas Culpeper and Francis Dereham are executed for having affairs with Catherine Howard, Queen of England and wife of Henry VIII of England e.g Henry VIII.
Famous Birthdays in 1541
26th January » Florent Chrestien, French poet (d. 1596)
8th April » Michele Mercati, Italian physician (d. 1593)
Famous Deaths in History for 1541
27th May » Margaret Pole, Countess of Salisbury (b. 1473)
26th June » Francisco Pizarro, Spanish explorer and politician (b. 1471)
4th July » Pedro de Alvarado, Spanish general and explorer (b. 1495)
1st August » Simon Grynaeus, German theologian and scholar (b. 1493)
24th September » Paracelsus, German-Swiss physician, botanist, and chemist (b. 1493)
18th October » Margaret Tudor, English wife of James IV of Scotland (b. 1489)
10th December » Thomas Culpeper, English courtier (b. 1514)