22nd January » The Ava Kingdom falls to the Taungoo Dynasty in what is now present-day Burma.
9th February » Bishop of Gloucester John Hooper (bishop) called John Hooper is burned at the stake.
25th March » The city of Valencia, Carabobo named Valencia is founded in present-day Venezuela.
17th April » After 18 months of siege, Siena surrenders to the Florence called Florentine-Holy Roman Empire named Imperial army. The Republic of Siena is incorporated into the Grand Duchy of Tuscany.
2nd July » The Ottoman Admiral Turgut Reis sacks the Italian city of Paola, Italy called Paola.
18th July » The College of Arms is reincorporated by Royal charter signed by Queen Mary I of England and King Philip II of Spain.
25th September » The Peace of Augsburg is signed in Augsburg by Charles V, Holy Roman Emperor named Charles V and the princes of the Schmalkaldic League.
1st November » French Huguenots establish the France Antarctique colony in present-day Rio de Janeiro, Brazil.
12th November » The English Parliament Established church or re-establishes Catholicism.